They are sedating, which means they’re likely to make you drowsy after you use them.They also don’t last as long in your system, so they require more frequent dosing than the newer generations.First-generation brands include Benadryl and Chlor-Trimeton. The first-generation antihistamine diphenhydramine is the main active ingredient in Benadryl.Benadryl helps relieve runny nose, sneezing, itchy or watery eyes, and nose or throat itching.Antihistamines work by decreasing the effects of histamine at certain cell receptors.Over-the-counter (OTC) antihistamines can help treat symptoms such as: First-generation OTC oral antihistamines, including diphenhydramine and chlorpheniramine, are the oldest group.You should also avoid drinking alcohol with any antihistamine because it can increase the side effect of drowsiness.The newer second-generation and third-generation OTC oral antihistamines were developed to target their action on more specific receptors.
Also, these drugs work longer in your body so you need fewer doses.
Other common OTC brands with cetirizine as the main active ingredient include: Loratadine is the main active ingredient in Claritin.
It helps relieve runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat due to hay fever and other upper respiratory allergies. It comes in a tablet, a tablet that dissolves in your mouth, a chewable tablet, a liquid-filled capsule, and a syrup.
These symptoms may be due to hay fever, other upper respiratory allergies, or the common cold.
Benadryl can also be used to treat hives and to reduce redness and itching.